Picking up prostitutes have been much the same for Grand Theft Auto III, Vice City, Liberty City Stories and Vice City Stories; simply by pulling up to one.
You can avail them given that you have more than 0, else they will refuse to get into the car (entering the cheat code to make pedestrians enter your car will only make them to stand).
You are unable to pick up prostitutes in emergency vehicles, bikes, or a bus, with Niko citing various reasons.
One other major change is that the camera angle is not fixed, and more suggestive animations are shown of the sexual acts between the player character and the prostitute, although both Niko and the prostitute will both be fully clothed (the animation is more clearly seen if a convertible is used).
This was broken in the PC version due to a randomizer error, but a mod or a third party patch can be used to fix it.
Since seclusion is now considered, when the car shakes at its fastest and anyone which is not a hooker comes near the car, the hooker will stop the service immediately and get out of the car.
Sometimes, the shaking won't stop if a car has overturned.
She claims that "Losers like you pay us working girls for a ride, then unload your guns in our faces just to get your filthy money back!
Having "sex" with a hooker is just an effect of the car bouncing up and down on an accelerating speed (specifically, the car lowers down on where the hooker is sitting).
Sex has a healing effect; it can restore up to 30 health points.
Niko also cannot have sex with prostitutes while in Emergency Vehicles, nor in certain vehicles due to size, saying things like "I bet you're flexible but not in here," or "I think this car is a little too small for that..." (although Niko will still say these quotes even if he's in an Emergency Vehicle).
Most prostitutes are seen in shorts or skirts and heels, they sometimes wear hats and usually have their hair up.